4-(2-Chloroethyl)morpholine → 3-Benzyl-4-(2'-morpholinoethoxy)-coumarin
反応式
[CH2:1]([C:8]1[C:9](=[O:19])[O:10][C:11]2[C:16]([C:17]=1[OH:18])=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[O:20]1[CH2:25][CH2:24][N:23]([CH2:26][CH2:27]Cl)[CH2:22][CH2:21]1>>[CH2:1]([C:8]1[C:9](=[O:19])[O:10][C:11]2[C:16]([C:17]=1[O:18][CH2:27][CH2:26][N:23]1[CH2:24][CH2:25][O:20][CH2:21][CH2:22]1)=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1参加物
3
実験手順
Prepared as indicated in Example 8, from 13.7 g. (0.54 mol) of 3-benzyl-4-hydroxy-coumarin and 10.6 g. (0.071 mol) of 2-morpholino-1-chlorethane. After evaporation of the chloroform, there are obtained 17 g. of an oil which cannot be crystallised. Yield 88.5% (theoretical yield 19.2 g.).
後処理
- customPrepared
- customAfter evaporation of the chloroform, there
- customare obtained 17 g
- customof an oil which cannot be crystallised