化工社化工社 化学情報印刷レポート · 研究参考用
Dimethylamine → {(2-Chloro-6-fluoro-phenyl)-[2-(4-chloro-phenyl)-1H-indol-3-yl]-methyl}-dimethyl-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethylamine | HCID 674 | — |
| 反応物 | 2-Chloro-6-fluorobenzaldehyde | HCID 67847 | — |
| 反応物 | 2-(4-Chlorophenyl)-1H-indole | HCID 220463 | — |
| 反応物 | (2-Chloro-6-fluoro-benzylidene)-dimethylammonium chloride | HCID 21985312 | — |
| 生成物 | {(2-Chloro-6-fluoro-phenyl)-[2-(4-chloro-phenyl)-1H-indol-3-yl]-methyl}-dimethyl-amine | HCID 21985282 | — |
反応手順
The preparation was carried out in accordance with general synthesis instructions 4 from 2-(4-chlorophenyl)-indole and (2-chloro-6-fluoro-benzylidene)-dimethyl-ammonium chloride, which had been prepared in accordance with example 24 from 2-chloro-6-fluoro-benzaldehyde and dimethylamine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07091220B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-481423226194464382ed5e4c678c6fee |
| 出典メモ | uspto-grants-2006_08 |