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Ethanol → 9,10-Bis(2-chloroethoxy)-2-methylanthracene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethanol | HCID 702 | — |
| 反応物 | Dichloromethane | HCID 6344 | — |
| 反応物 | Ethanol, 2-chloro-, 1-(4-methylbenzenesulfonate) | HCID 6639 | — |
| 反応物 | 2-Methylanthraquinone | HCID 6773 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 触媒 | Zinc | HCID 23994 | — |
| 生成物 | 9,10-Bis(2-chloroethoxy)-2-methylanthracene | HCID 13305449 | — |
反応手順
A 22.2 g. portion of 2-methylanthraquinone is reduced with 10 g. of zinc and 200 ml. of 20% sodium hydroxide in 40 ml. of ethanol, then alkylated with 50 ml. of 2-chloroethyl-p-toluene sulfonate as described in Example 1. The crude product is taken up in methylene chloride, filtered, dried over magnesium sulfate and concentrated to dryness. Recrystallization from 100 ml. of propanol gives 0.7 g. of the desired intermediate as a yellow solid, m.p. 82°-85° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04419354 |
| 出典データセット | uspto-grants-1983_12 |
| ORD ID | ord-a2e409b794a84f0095c4e2829b1c4c8a |
| 出典メモ | uspto-grants-1983_12 |