Potassium Carbonate → 4-(Phenylsulfamoyl)phenyl 4-ethenylbenzoate

HRID 904929ノート

反応式

HRID 904929 の反応式
Br[CH2:2][CH2:3][C:4]1[CH:28]=[CH:27][C:7]([C:8]([O:10][C:11]2[CH:16]=[CH:15][C:14]([S:17](=[O:26])(=[O:25])[NH:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)=[CH:13][CH:12]=2)=[O:9])=[CH:6][CH:5]=1.C(=O)([O-])[O-].[K+].[K+]>CC(C)=O>[CH:3]([C:4]1[CH:28]=[CH:27][C:7]([C:8]([O:10][C:11]2[CH:16]=[CH:15][C:14]([S:17](=[O:25])(=[O:26])[NH:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)=[CH:13][CH:12]=2)=[O:9])=[CH:6][CH:5]=1)=[CH2:2]

参加物

4

反応物 2

HCID 11430Potassium CarbonateHCID 204418094-(Phenylsulfamoyl)phenyl 4-(2-bromoethyl)benzoate

生成物 1

HCID 204418184-(Phenylsulfamoyl)phenyl 4-ethenylbenzoate収率 76.7%

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

A mixture of 18.5 g (0.0402 mol) of 4-(N-phenylsulfamoyl)phenyl 4-(2-bromoethyl)benzoate, 5.55 g (0.0402 mol) of potassium carbonate and 250 ml of acetone was stirred at room temperature for approximately 48 hours. The mixture was filtered and concentrated to an oily solid. Recrystallization from ethanol:water gave 11.7 g (76.6% of theory) of 4-(N-phenylsulfamoyl)phenyl 4-vinylbenzoate; mp=59°-60° C.

後処理

  1. filtrationThe mixture was filtered
  2. concentrationconcentrated to an oily solid
  3. customRecrystallization from ethanol

出典と根拠

ORDレコード
ord-ed67e76bc3574af3b78669eba4be5046
出典データセット
uspto-grants-1983_12
特許番号
US04420630

反応ノート

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