Dimethylamine → [(2,4-Dichloro-phenyl)-(1-methyl-1H-indol-3-yl)-methyl]-dimethyl-amine

HRID 9050

反応式

HRID 9050 の反応式
[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3]1.[Cl-].[Cl:12][C:13]1[CH:22]=[C:21]([Cl:23])[CH:20]=[CH:19][C:14]=1[CH:15]=[N+:16]([CH3:18])[CH3:17].ClC1C=C(Cl)C=CC=1C=O.CNC>>[Cl:12][C:13]1[CH:22]=[C:21]([Cl:23])[CH:20]=[CH:19][C:14]=1[CH:15]([N:16]([CH3:18])[CH3:17])[C:4]1[C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[N:2]([CH3:1])[CH:3]=1

参加物

5

反応物 4

HCID 674DimethylamineHCID 117811-MethylindoleHCID 134042,4-DichlorobenzaldehydeHCID 21985378(2,4-Dichloro-benzylidene)-dimethyl-ammonium chloride

生成物 1

HCID 21985335[(2,4-Dichloro-phenyl)-(1-methyl-1H-indol-3-yl)-methyl]-dimethyl-amine

実験手順

The preparation was carried out in accordance with general synthesis instructions 4 from 1-methylindole and (2,4-dichloro-benzylidene)-dimethyl-ammonium chloride, which had been prepared in accordance with example 24 from 2,4-dichloro-benzaldehyde and dimethylamine.

出典と根拠

ORDレコード
ord-a77eb8032c0644bdbcdf6b13a2b295cc
出典データセット
uspto-grants-2006_08
特許番号
US07091220B2

関連ノート

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