2-Methylbenzenesulfonic acid → 1-(3-Ethyl-5-methyl-4-isoxazolyl)-1-ethanone phenyl hydrazone
反応式
[C:1]([C:4]1[C:5]([CH2:10][CH3:11])=[N:6][O:7][C:8]=1[CH3:9])(=O)[CH3:2].[C:12]1([NH:18][NH2:19])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.C1(C)C(S(O)(=O)=O)=CC=CC=1>C(O)C>[C:12]1([NH:18][N:19]=[C:1]([C:4]2[C:5]([CH2:10][CH3:11])=[N:6][O:7][C:8]=2[CH3:9])[CH3:2])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1参加物
5
実験手順
A mixture of 61.1 g. (0.4 mole) of 4-acetyl-3-ethyl-5-methyl-isoxazole, 39.4 ml. (0.4 mole) of phenyl hydrazine and 500 mg. toluenesulfonic acid in 400 ml. ethanol is stirred at room temperature for 48 hours. The resulting solid is filtered and washed with cold ether to give 1-(3-ethyl-5-methyl-4-isoxazolyl)-1-ethanone phenyl hydrazone; m.p. 72° to 75° C.
後処理
- additionA mixture of 61.1 g
- filtrationThe resulting solid is filtered
- washwashed with cold ether
出典と根拠
- ORDレコード
- ord-eff9086a13bf445ab901c5d172f88de3
- 出典データセット
- uspto-grants-1983_12
- 特許番号
- US04421752
反応ノート
読み込み中…