Bromine → 4-(Bromomethyl)-2-fluoro-1,1′-biphenyl
反応式
[F:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.[Br:15]Br>>[F:1][C:2]1[CH:7]=[C:6]([CH2:8][Br:15])[CH:5]=[CH:4][C:3]=1[C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1参加物
3
実験手順
In this instance the 2-fluoro-4-methylbiphenyl was heated to 140° to 170° C. with a heating mantle and under irradiation with light without a solvent while one equivalent of Br2 was added dropwise. Subsequent NMR analysis showed the starting material:monobromide:dibromide ratio to be 25:58:18.
後処理
- additionwas added dropwise
出典と根拠
- ORDレコード
- ord-e5425470cfd14ddaba53d270b31aa857
- 出典データセット
- uspto-grants-1983_12
- 特許番号
- US04422979
反応ノート
読み込み中…