Methyl chloroacetate → HCID 13241588、化合物

反応式

[CH2:1]([O:3][P:4]([CH2:9][NH:10][CH:11]=[O:12])(=[O:8])[O:5][CH2:6][CH3:7])[CH3:2].[CH3:13][O:14][C:15](=[O:18])[CH2:16]Cl>>[CH3:13][O:14][C:15](=[O:18])[CH2:16][N:10]([CH2:9][P:4]([O:3][CH2:1][CH3:2])([O:5][CH2:6][CH3:7])=[O:8])[CH:11]=[O:12]

参加物

反応物 2

HCID 7295Methyl chloroacetate

HCID 12673118Phosphonic acid, [(formylamino)methyl]-, diethyl ester

生成物 1

HCID 13241588HCID 13241588、化合物

実験手順

The process in the third step of the process of the invention comprises reacting diethyl-N-(formyl)aminomethylphosphonate with methylchloroacetate in the presence of a proton-extracting base and a suitable solvent to produce N-(diethylphosphonomethyl)-N-(formyl)glycine methyl ester.

出典と根拠

ORDレコード: ord-5ee8c5a12651445a8837fb77b8c79acf
出典データセット: uspto-grants-1983_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04422982

反応ノート

読み込み中…