化工社化工社 化学情報印刷レポート · 研究参考用
Dimethylamine → [(2-Chloro-4-fluoro-phenyl)-(2-methyl-1H-indol-3-yl)-methyl]-dimethyl-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethylamine | HCID 674 | — |
| 反応物 | 2-Methylindole | HCID 7224 | — |
| 反応物 | 2-Chloro-4-fluorobenzaldehyde | HCID 145024 | — |
| 反応物 | (2-Chloro-4-fluoro-benzylidene)-dimethylammonium chloride | HCID 21985315 | — |
| 生成物 | [(2-Chloro-4-fluoro-phenyl)-(2-methyl-1H-indol-3-yl)-methyl]-dimethyl-amine | HCID 21985360 | — |
反応手順
The preparation was carried out in accordance with general synthesis instructions 4 from 2-methyl-1H-indole and (2-chloro-4-fluoro-benzylidene)-dimethylammonium chloride, which had been prepared in accordance with example 44 from 2-chloro-4-fluoro-benzaldehyde and dimethylamine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07091220B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-f9cc66bc533c45fc829f8836d582b65f |
| 出典メモ | uspto-grants-2006_08 |