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HRID 9053作成日:2026年10月24日

Dimethylamine → [(2-Chloro-6-fluoro-phenyl)-(2-methyl-1H-indol-3-yl)-methyl]-dimethyl-amine

https://huagongshe.com/ja/reaction/9053

反応式

関与物質

役割名称HCID仕込み量
反応物DimethylamineHCID 674—
反応物2-MethylindoleHCID 7224—
反応物2-Chloro-6-fluorobenzaldehydeHCID 67847—
反応物(2-Chloro-6-fluoro-benzylidene)-dimethylammonium chlorideHCID 21985312—
生成物[(2-Chloro-6-fluoro-phenyl)-(2-methyl-1H-indol-3-yl)-methyl]-dimethyl-amineHCID 21985351—

反応手順

The preparation was carried out in accordance with general synthesis instructions 4 from 2-methyl-1H-indole and (2-chloro-6-fluoro-benzylidene)-dimethylammonium chloride, which had been prepared in accordance with example 44 from 2-chloro-6-fluoro-benzaldehyde and dimethylamine.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07091220B2
出典データセットuspto-grants-2006_08
ORD IDord-f85e5808d5ab42c3a61017baad9dc05f
出典メモuspto-grants-2006_08