化工社化工社 化学情報印刷レポート · 研究参考用
Triethylamine → Methanesulphonylpyrazoline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Methanesulfonyl chloride | HCID 31297 | — |
| 反応物 | 2,3-dihydro-1H-pyrazole | HCID 4156003 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | Methanesulphonylpyrazoline | HCID 54062380 | 77% |
反応手順
114.5 g of methanesulphonic acid chloride were added dropwise to 70 g of pyrazoline and 101 g of triethylamine in 300 ml of methylene chloride at room temperature. The mixture was subsequently stirred at room temperature for 3 hours and was filtered. The filtrate was washed with water, dried over sodium sulphate and concentrated. 114 g (77% of theory) of methanesulphonylpyrazoline of melting point 62° C. were obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04423225 |
| 出典データセット | uspto-grants-1983_12 |
| ORD ID | ord-a07ead0b1aaa4c1bb2f33c4ae7d2feac |
| 出典メモ | uspto-grants-1983_12 |