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Benzene → 3-Chlorobiphenyl
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzene | HCID 241 | — |
| 反応物 | 3-Chloroaniline | HCID 7932 | — |
| 反応物 | Tert-Butyl nitrite | HCID 10906 | — |
| 触媒 | Copper | HCID 23978 | — |
| 生成物 | 3-Chlorobiphenyl | HCID 16322 | 67.6% |
反応手順
In a manner similar to Example 1, the reaction of 3-chloroaniline (38.3 g, 0.30 mole) with t-butyl nitrite (46.4 g, 0.45 mole) in the presence of copper powder (15.0 g, 0.24 mole) and 4Å molecular sieves (powdered, 15.0 g) in benzene (1650 ml) produced 3-chloro[1,1'-biphenyl] (38.4 g, 67.6% yield, bp 96°/0.15 mm) as an oil. When the experiment was repeated the yield was 65.7%
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04423234 |
| 出典データセット | uspto-grants-1983_12 |
| ORD ID | ord-6a1a366cf55c4837bb35d83c4d83a7a9 |
| 出典メモ | uspto-grants-1983_12 |