化工社化工社 化学情報印刷レポート · 研究参考用
Acetic Anhydride → 2-Pyrrolidinone, 1-acetyl-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Anhydride | HCID 7918 | — |
| 反応物 | 2-Pyrrolidone | HCID 12025 | — |
| 生成物 | 2-Pyrrolidinone, 1-acetyl- | HCID 70266 | 96% |
反応手順
A mixture of 112 g of 2-pyrrolidinone (9) and 249 mL of acetic anhydride was heated at reflux for 2 hours. The resultant mixture was allowed to cool to room temperature, was concentrated in vacuo, and was distilled (0.8 mm Hg, 68° C.) to provide 160 g of N-acetyl-2-pyrrolidinone (4) in 96% yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08012969B2 |
| 出典データセット | uspto-grants-2011_09 |
| ORD ID | ord-8d502b49ae6b464793197a75442691c1 |
| 出典メモ | uspto-grants-2011_09 |