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Dimethylamine → [(3,4-Dimethoxy-phenyl)-[2-(4-fluoro-phenyl)-1H-indol-3-yl]-methyl]-dimethylamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethylamine | HCID 674 | — |
| 反応物 | Veratraldehyde | HCID 8419 | — |
| 反応物 | 2-(4-Fluorophenyl)indole | HCID 136622 | — |
| 反応物 | (3,4-Dimethoxy-benzylidene)-dimethylammonium chloride | HCID 21985355 | — |
| 生成物 | [(3,4-Dimethoxy-phenyl)-[2-(4-fluoro-phenyl)-1H-indol-3-yl]-methyl]-dimethylamine | HCID 21985283 | — |
反応手順
The preparation was carried out in accordance with general synthesis instructions 4 from 2-(4-fluoro-phenyl)-1H-indole and (3,4-dimethoxy-benzylidene)-dimethylammonium chloride, which had been prepared in accordance with example 44 from 3,4-dimethoxy-benzaldehyde and dimethylamine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07091220B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-17043a3bab16407eb42e2bd7bcec8beb |
| 出典メモ | uspto-grants-2006_08 |