Dimethylamine → [(4-Fluoro-phenyl)-(4-methyl-1H-indol-3-yl)-methyl]-dimethyl-amine

HRID 9064

反応式

HRID 9064 の反応式
[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH:4]=[CH:5][NH:6]2.[Cl-].[F:12][C:13]1[CH:22]=[CH:21][C:16]([CH:17]=[N+:18]([CH3:20])[CH3:19])=[CH:15][CH:14]=1.FC1C=CC(C=O)=CC=1.CNC>>[F:12][C:13]1[CH:14]=[CH:15][C:16]([CH:17]([N:18]([CH3:20])[CH3:19])[C:4]2[C:3]3[C:7](=[CH:8][CH:9]=[CH:10][C:2]=3[CH3:1])[NH:6][CH:5]=2)=[CH:21][CH:22]=1

参加物

5

実験手順

The preparation was carried out in accordance with general synthesis instructions 4 from 4-methyl-1H-indole and (4-fluoro-benzylidene)-dimethylammonium chloride, which had been prepared in accordance with example 44 from 4-fluoro-benzaldehyde and dimethylamine.

出典と根拠

ORDレコード
ord-e8415c5d0b5f45968db469e1e4e5f5f1
出典データセット
uspto-grants-2006_08
特許番号
US07091220B2

関連ノート

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