Potassium Carbonate → (3R)-tert-Butyl 4-((6-(5-(cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl)-2-(3-hydroxy-2,2-dimethylpropyl)-1-oxo-1,2-dihydroisoquinolin-4-yl)methyl)-3-methylpiperazine-1-carboxylate

反応式

[CH:1]1([NH:4][C:5]([C:7]2[CH:8]=[C:9]([F:52])[C:10]([CH3:51])=[C:11]([C:13]3[CH:14]=[C:15]4[C:20](=[CH:21][CH:22]=3)[C:19](=[O:23])[N:18]([CH2:24][C:25]([CH3:35])([CH3:34])[CH2:26][O:27]C(=O)C(C)(C)C)[CH:17]=[C:16]4[CH2:36][N:37]3[CH2:42][CH2:41][N:40]([C:43]([O:45][C:46]([CH3:49])([CH3:48])[CH3:47])=[O:44])[CH2:39][C@H:38]3[CH3:50])[CH:12]=2)=[O:6])[CH2:3][CH2:2]1.C(=O)([O-])[O-].[K+].[K+]>CO.O>[CH:1]1([NH:4][C:5]([C:7]2[CH:8]=[C:9]([F:52])[C:10]([CH3:51])=[C:11]([C:13]3[CH:14]=[C:15]4[C:20](=[CH:21][CH:22]=3)[C:19](=[O:23])[N:18]([CH2:24][C:25]([CH3:34])([CH3:35])[CH2:26][OH:27])[CH:17]=[C:16]4[CH2:36][N:37]3[CH2:42][CH2:41][N:40]([C:43]([O:45][C:46]([CH3:49])([CH3:48])[CH3:47])=[O:44])[CH2:39][C@H:38]3[CH3:50])[CH:12]=2)=[O:6])[CH2:3][CH2:2]1