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HRID 9081作成日:2026年10月26日

Dimethylamine → Dimethyl-[(2-methyl-1H-indol-3-yl)-(4-trifluoromethyl-phenyl)-methyl]-amine

https://huagongshe.com/reaction/9081

反応式

関与物質

役割名称HCID仕込み量
反応物DimethylamineHCID 674—
反応物2-MethylindoleHCID 7224—
反応物4-(Trifluoromethyl)benzaldehydeHCID 67996—
反応物(4-Trifluoromethyl-benzylidene)-dimethylammonium chlorideHCID 21985290—
生成物Dimethyl-[(2-methyl-1H-indol-3-yl)-(4-trifluoromethyl-phenyl)-methyl]-amineHCID 21985302—

反応手順

The preparation was carried out in accordance with general synthesis instructions 4 from 2-methyl-1H-indole and (4-trifluoromethyl-benzylidene)-dimethylammonium chloride, which had been prepared in accordance with example 44 from 4-trifluoromethyl-benzaldehyde and dimethylamine.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07091220B2
出典データセットuspto-grants-2006_08
ORD IDord-4dfdeeb8dda1463f9bf2481d09e0218e
出典メモuspto-grants-2006_08