Methylamine → N-Methyl-4-(2-oxopropyl)benzene-1-sulfonamide

反応式

[O:1]=[C:2]([CH3:14])[CH2:3][C:4]1[CH:9]=[CH:8][C:7]([S:10]([NH2:13])(=[O:12])=[O:11])=[CH:6][CH:5]=1.[CH3:15]N>>[CH3:15][NH:13][S:10]([C:7]1[CH:6]=[CH:5][C:4]([CH2:3][C:2](=[O:1])[CH3:14])=[CH:9][CH:8]=1)(=[O:11])=[O:12]

参加物

反応物 2

HCID 6329Methylamine

HCID 215301384-(2-Oxopropyl)benzene-1-sulfonamide

生成物 1

HCID 58436479N-Methyl-4-(2-oxopropyl)benzene-1-sulfonamide

実験手順

4-(2-Oxo-propyl)-benzenesulfonyl chloride (prepared as described in European patent specification EP 91749 A2) (0.087 g, 4.1 mmol) was treated with methylamine to give the title compound.

出典と根拠

ORDレコード: ord-15711718751c49ea9674f2074f50db9a
出典データセット: uspto-grants-2011_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08017608B2

反応ノート

読み込み中…