化工社化工社 化学情報印刷レポート · 研究参考用
Water → Triphenylsulfonium 2-pivaloyloxy-1,1-difluoroethanesulfonate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Triphenylsulfonium iodide | HCID 21881071 | — |
| 反応物 | Sodium 2-pivaloyloxy-1,1-difluoroethanesulfonate | HCID 57817346 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | Triphenylsulfonium 2-pivaloyloxy-1,1-difluoroethanesulfonate | HCID 86632753 | 95% |
反応手順
In 700 g of dichloromethane and 400 g of water were dissolved 159 g (0.37 mole) of sodium 2-(pivaloyloxy)-1,1-difluoroethanesulfonate (purity 63%) and 132 g (0.34 mole) of triphenylsulfonium iodide. The organic layer was separated, washed three times with 200 g of water, and concentrated. Diethyl ether was added to the residue for recrystallization, obtaining the target compound as white crystals. 164 g (yield 95%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08021822B2 |
| 出典データセット | uspto-grants-2011_09 |
| ORD ID | ord-6db70fc4d5b04378b7d38d41472ce010 |
| 出典メモ | uspto-grants-2011_09 |