化工社化工社 化学情報印刷レポート · 研究参考用
Ammonia → N-p-Bromophenylthiourea
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ammonia | HCID 222 | — |
| 反応物 | 4-Bromophenyl isothiocyanate | HCID 16133 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | N-p-Bromophenylthiourea | HCID 2735620 | — |
反応手順
4-Bromophenylisothiocyanate (21.4 g) was dissolved in tetrahydrofuran (50 mL), and concentrated aqueous ammonia (28%) (13.7 mL) was added dropwise to the solution, followed by stirring at room temperature for 10 minutes. The solvent was concentrated under reduced pressure, and the crystals were recovered through filtration by use of water, followed by recrystallization from ethanol, to thereby yield the title compound (16.4 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08022075B2 |
| 出典データセット | uspto-grants-2011_09 |
| ORD ID | ord-21dc0986b22b4059a3b8ea7a202da54c |
| 出典メモ | uspto-grants-2011_09 |