関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | 2-Amino-5-bromobenzene-1-thiol | HCID 1209045 | — |
| 反応物 | 4-(5-Oxazolyl)benzaldehyde | HCID 10583346 | — |
| 溶媒 | Dimethyl Sulfoxide | HCID 679 | — |
| 生成物 | 5-[4-(6-Bromo-1,3-benzothiazol-2-yl)phenyl]-1,3-oxazole | HCID 67405287 | 58.8% |
反応手順
2 Amino-5-bromobenzenethiol (102 mg) and 4-(1,3-oxazol-5-yl)benzaldehyde (87 mg) were dissolved in dimethylsulfoxide (1 mL), followed by stirring at 160° C. for 10 minutes. Water (10 mL) was added to the reaction mixture. The precipitated matter was recovered through filtration, and washed with methanol, to thereby yield the title compound (105 mg).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08022075B2 |
|---|
| 出典データセット | uspto-grants-2011_09 |
|---|
| ORD ID | ord-0e754375d48d4d6aa7a3d6b803037183 |
|---|
| 出典メモ | uspto-grants-2011_09 |
|---|
