2-Methyl-4-(morpholin-4-yl)aniline → 4-(2-Amino-pyrimidin-5-yl)-2-morpholin-4-yl-5,6-dihydro-pyrrolo[2,3-d]pyrimidine-7-carboxylic acid (2-methyl-4-morpholin-4-yl-phenyl)-amide

反応式

COC1C=CC(CN(CC2C=CC(OC)=CC=2)C2N=CC(C3C4CCNC=4N=C(N4CCOCC4)N=3)=CN=2)=CC=1.CC1C=C(N2CCOCC2)C=CC=1N.[CH3:55][C:56]1[CH:61]=[C:60]([N:62]2[CH2:67][CH2:66][O:65][CH2:64][CH2:63]2)[CH:59]=[CH:58][C:57]=1[NH:68][C:69]([N:71]1[C:75]2[N:76]=[C:77]([N:105]3[CH2:110][CH2:109][O:108][CH2:107][CH2:106]3)[N:78]=[C:79]([C:80]3[CH:81]=[N:82][C:83]([N:86](CC4C=CC(OC)=CC=4)CC4C=CC(OC)=CC=4)=[N:84][CH:85]=3)[C:74]=2[CH2:73][CH2:72]1)=[O:70]>>[CH3:55][C:56]1[CH:61]=[C:60]([N:62]2[CH2:63][CH2:64][O:65][CH2:66][CH2:67]2)[CH:59]=[CH:58][C:57]=1[NH:68][C:69]([N:71]1[C:75]2[N:76]=[C:77]([N:105]3[CH2:110][CH2:109][O:108][CH2:107][CH2:106]3)[N:78]=[C:79]([C:80]3[CH:81]=[N:82][C:83]([NH2:86])=[N:84][CH:85]=3)[C:74]=2[CH2:73][CH2:72]1)=[O:70]