Acetic Anhydride → N-(3,5-dimethoxyphenyl)acetamide

HRID 912548

反応式

HRID 912548 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([NH2:11])[CH:6]=[C:7]([O:9][CH3:10])[CH:8]=1.[CH3:12][C:13](OC(C)=O)=[O:14].CCCCCC>C1(C)C=CC=CC=1>[CH3:10][O:9][C:7]1[CH:6]=[C:5]([NH:11][C:13](=[O:14])[CH3:12])[CH:4]=[C:3]([O:2][CH3:1])[CH:8]=1

参加物

5

反応物 3

HCID 7918Acetic AnhydrideHCID 8058HexaneHCID 663013,5-Dimethoxyaniline

生成物 1

HCID 702039N-(3,5-dimethoxyphenyl)acetamide

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

To a solution of 3,5-dimethoxy-phenylamine (22.0 g, 143.6 mmol) in toluene (100 mL), is added slowly Ac2O (14 mL) at room temperature. After stirring 30 minutes, hexane (50 mL) is added with stirring at room temperature. The resulting solid is filtered and washed with hexane (50 mL) to offer designed product as a white solid 14.

後処理

  1. stirringwith stirring at room temperature
  2. filtrationThe resulting solid is filtered
  3. washwashed with hexane (50 mL)

出典と根拠

ORDレコード
ord-64bcb4283a7945a9bd9298d6aa0737d0
出典データセット
uspto-grants-2011_09
特許番号
US08026243B2

関連ノート

読み込み中…