Ammonia → HCID 178514164、化合物
反応式
[N:1]1[NH:2][C:3](NC)=[CH:4][CH:5]=1.[C:8]([N:16]=[C:17]=[S:18])(=O)C1C=CC=CC=1.[NH3:19]>CO>[NH:1]1[CH:5]=[CH:4][C:3]([CH2:8][NH:16][C:17]([NH2:19])=[S:18])=[N:2]1参加物
5
実験手順
The title compound was prepared in accordance with the general method described in Example 12(a) by using 2H-pyrazol-3-yl-methylamine (1.20 g, 12.4 mmol), benzoyl isothiocyanate (1.8 mL, 13.6 mmol) and ammonia in methanol (7N, 60 mL) with the exception that the crude product isolated by filtration (1.39 g, 72% yield) was used in the next step without further purification. MS (ESI) m/z 157 (M+1)
後処理
- customisolated by filtration (1.39 g, 72% yield)
- customwas used in the next step without further purification
出典と根拠
- ORDレコード
- ord-4e26e5919d2b42cf8a9cf0d7caae231b
- 出典データセット
- uspto-grants-2011_09
- 特許番号
- US08026244B2
反応ノート
読み込み中…