関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Stavudine DMPU | HCID 86625622 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | Stavudine | HCID 18283 | 66.82% |
反応手順
Stavudine DMPU solvate (20 g, 0.057 mole) is dissolved in water (20 ml) at 55° C. and the solution is allowed cooling on its own for an hour to crystallize. The mixture is further cooled on 0-5° C. for 2 hrs. The precipitated product is filtered, washed with acetone and dried to give 8.5 g (66.82%) of pure white crystalline Stavudine. HPLC results are given in Table-2
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08026356B2 |
|---|
| 出典データセット | uspto-grants-2011_09 |
|---|
| ORD ID | ord-c22b27eb05fb4b52934752f5d42be106 |
|---|
| 出典メモ | uspto-grants-2011_09 |
|---|
