tert-Butyl bromoacetate → 1,1-Dimethylethyl [4-chloro-5-cyano-2-(trifluoromethyl)-1H-benzimidazol-1-yl]acetate

HRID 913581ノート

反応式

HRID 913581 の反応式
[Cl:1][C:2]1[C:10]2[N:9]=[C:8]([C:11]([F:14])([F:13])[F:12])[NH:7][C:6]=2[CH:5]=[CH:4][C:3]=1[C:15]#[N:16].Br[CH2:18][C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20]>>[Cl:1][C:2]1[C:10]2[N:9]=[C:8]([C:11]([F:12])([F:13])[F:14])[N:7]([CH2:18][C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20])[C:6]=2[CH:5]=[CH:4][C:3]=1[C:15]#[N:16]

参加物

3

反応物 2

HCID 79177tert-Butyl bromoacetateHCID 674045324-chloro-2-(trifluoromethyl)-1H-benzimidazole-5-carbonitrile

生成物 1

HCID 690337571,1-Dimethylethyl [4-chloro-5-cyano-2-(trifluoromethyl)-1H-benzimidazol-1-yl]acetate

実験手順

Synthesized as described in Example 200A from 4-chloro-2-(trifluoromethyl)-1H-benzimidazole-5-carbonitrile and 1,1-dimethylethyl bromoacetate: MS (APCl) m/z 360 (M+1).

後処理

  1. customSynthesized

出典と根拠

ORDレコード
ord-ecbc34fbde244caeb86c9af1e5553390
出典データセット
uspto-grants-2011_09
特許番号
US08026262B2

反応ノート

読み込み中…