戻る
化工社化工社 化学情報印刷レポート · 研究参考用
HRID 913712作成日：2026年10月27日

3,5-Bis-trifluoromethylphenylboronic acid → 1-{[3',5'-bis(Trifluoromethyl)-3-biphenylyl]methyl}-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

https://huagongshe.com/reaction/913712

反応式

関与物質

役割名称HCID仕込み量
反応物3,5-Bis-trifluoromethylphenylboronic acidHCID 156265—
反応物1-[(3-Bromophenyl)methyl]-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 67405035—
生成物1-{[3',5'-bis(Trifluoromethyl)-3-biphenylyl]methyl}-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 86620704—

反応手順

Synthesized as described in Example 310D using 1-[(3-bromophenyl)methyl]-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile (Example 318A) and [3,5-bis(trifluoromethyl)phenyl]boronic acid: MS (ES) m/z 527 (M+1).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08026262B2
出典データセットuspto-grants-2011_09
ORD IDord-07284c2369c844638e1d5a79c921c88e
出典メモuspto-grants-2011_09