Aluminium lithium hydride → [2-ethyl-5-(4-trifluoromethyl-phenyl)-2H-pyrazol-3-yl]-methanol

HRID 915410

反応式

HRID 915410 の反応式
C([O:3][C:4]([C:6]1[N:7]([CH2:21][CH3:22])[N:8]=[C:9]([C:11]2[CH:16]=[CH:15][C:14]([C:17]([F:20])([F:19])[F:18])=[CH:13][CH:12]=2)[CH:10]=1)=O)C.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[CH2:21]([N:7]1[C:6]([CH2:4][OH:3])=[CH:10][C:9]([C:11]2[CH:16]=[CH:15][C:14]([C:17]([F:19])([F:18])[F:20])=[CH:13][CH:12]=2)=[N:8]1)[CH3:22]

参加物

3

反応物 2

HCID 21226445Aluminium lithium hydrideHCID 667778182-ethyl-5-(4-trifluoromethyl-phenyl)-2H-pyrazole-3-carboxylic acid ethyl ester

生成物 1

HCID 69280245[2-ethyl-5-(4-trifluoromethyl-phenyl)-2H-pyrazol-3-yl]-methanol

実験手順

In analogy to the procedure described for example 1 a], 2-ethyl-5-(4-trifluoromethyl-phenyl)-2H-pyrazole-3-carboxylic acid ethyl ester was reduced with lithium aluminium hydride to give [2-ethyl-5-(4-trifluoromethyl-phenyl)-2H-pyrazol-3-yl]-methanol as colorless crystals.

出典と根拠

ORDレコード
ord-cdcb575acd194ec69c1d79db50eb7449
出典データセット
uspto-grants-2007_09
特許番号
US07265149B2

関連ノート

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