関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 2-Propynoic acid, 3-phenyl-, ethyl ester | HCID 91516 | — |
| 反応物 | 4-Phenyl-1,3-oxazole | HCID 589279 | — |
| 溶媒 | Ethyl Acetate | HCID 8857 | — |
| 生成物 | Ethyl-4-phenyl-3-furoate | HCID 15037153 | 78.4% |
反応手順
Mix 4-Phenyl oxazole (3.33 g, 23.0 mmol) and ethyl phenylpropiolate (4.0 g, 23.0 mmol) in a sealed tube and heat at 220° C. for 20 hours. Perform flash-chromatography on silica gel eluting with 4:1 Hex/ethyl acetate to afford 3.9 g of 4-phenylfuran-3-carboxylic acid ethyl ester as a yellow oil. MS: m/e=217 (MH+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07265246B2 |
|---|
| 出典データセット | uspto-grants-2007_09 |
|---|
| ORD ID | ord-9fd118029536481387b3a1242356d996 |
|---|
| 出典メモ | uspto-grants-2007_09 |
|---|
