Carbon tetrabromide → HCID 69385416、化合物
反応式
[C:1]([O:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([CH2:11][CH2:12][CH2:13][CH2:14]O)[CH:6]=1)(=[O:3])[CH3:2].C(Br)(Br)(Br)[Br:17].C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>C(Cl)Cl>[C:1]([O:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([CH2:11][CH2:12][CH2:13][CH2:14][Br:17])[CH:6]=1)(=[O:3])[CH3:2]参加物
5
実験手順
A solution of 3-(4-hydroxybutyl)phenyl acetate (416 mg) in DCM (10 mL) was treated with carbon tetrabromide (1.16 g) and triphenylphosphine (791 mg) and stirred at room temperature for 15 min prior to concentration in vacuo. The residue was purified by chromatography (SPE, DCM-petrol 1:1) to give the title compound. LCMS RT=3.58 min
後処理
- concentrationto concentration in vacuo
- customThe residue was purified by chromatography (SPE, DCM-petrol 1:1)
出典と根拠
- ORDレコード
- ord-5c0f3dec3e8b4df8aff65ef2f6eb4085
- 出典データセット
- uspto-grants-2007_09
- 特許番号
- US07271197B2
反応ノート
読み込み中…