Dimethylformamide → Sorafenib

反応式

[CH2:17]([N:18]([CH2:19][CH3:20])[CH2:21][CH3:22])[CH3:23].[CH:42]([N:43]([CH3:44])[CH3:45])=[O:46].[Cl:1][c:2]1[c:3]([C:13]([F:14])([F:15])[F:16])[cH:4][c:5]([NH:8][C:9](=[O:10])[NH:11][OH:12])[cH:6][cH:7]1.[NH2:24][c:25]1[cH:26][cH:27][c:28]([O:29][c:30]2[cH:31][c:32]([C:36](=[O:37])[NH:38][CH3:39])[n:33][cH:34][cH:35]2)[cH:40][cH:41]1>>[Cl:1][c:2]1[c:3]([C:13]([F:14])([F:15])[F:16])[cH:4][c:5]([NH:8][C:9](=[O:10])[NH:11][c:25]2[cH:26][cH:27][c:28]([O:29][c:30]3[cH:31][c:32]([C:36](=[O:37])[NH:38][CH3:39])[n:33][cH:34][cH:35]3)[cH:40][cH:41]2)[cH:6][cH:7]1