Hydrazine → 3,5-Diphenyl-1H-pyridazin-4-one

HRID 917813ノート

反応式

HRID 917813 の反応式
C([N:3](CC)[CH:4]=[C:5]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:6](=[O:15])[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=O)C.[NH2:24]N>C(O)(C)C>[C:9]1([C:7]2[C:6](=[O:15])[C:5]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[CH:4][NH:3][N:24]=2)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

参加物

4

反応物 2

HCID 9321HydrazineHCID 539328324-(Diethylamino)-1,3-diphenylbut-3-ene-1,2-dione

生成物 1

HCID 6192033,5-Diphenyl-1H-pyridazin-4-one

試薬・触媒・溶媒 1

HCID 3776Isopropanol溶媒

実験手順

The product solution from Example 1 was cooled to 0°C. and mixed with 20 ml. of isopropyl alcohol and 2 ml. of hydrazine. The mixture was stirred for 10 minutes, and was then warmed to room temperature and stirred for 15 hours. The product was then collected by filtration. The yield was 6.0 g. of 3,5-diphenyl-4(1H)-pyridazinone, m.p. 328°-32°C., which was identified by infrared and nuclear magnetic resonance analysis.

後処理

  1. additionmixed with 20 ml
  2. stirringstirred for 15 hours
  3. filtrationThe product was then collected by filtration

出典と根拠

ORDレコード
ord-34e2931cac64401982439a3cc562be6e
出典データセット
uspto-grants-1976_07
特許番号
US03967952

反応ノート

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