Methanethiol → HCID 178484946、化合物

HRID 917996ノート

反応式

HRID 917996 の反応式
[C:1]1([CH2:7][CH2:8][NH2:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[IH:10].[CH3:11][NH:12][C:13](=[N:16][CH3:17])SC.CS>C(O)C>[IH:10].[CH3:11][NH:12][C:13]([NH:16][CH3:17])=[N:9][CH2:8][CH2:7][C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

5

反応物 3

HCID 878MethanethiolHCID 1001PhenethylamineHCID 2775205Methyl N,N'-dimethylcarbamimidothioate--hydrogen iodide (1/1)

生成物 1

HCID 178484946HCID 178484946、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

2-phenylethylamine (2.4 g.), N,N',S-trimethylisothiourea hydriodide (4.92 g.) and ethanol (70 ml.), were boiled together under reflux for eight hours; methyl mercaptan was evolved. The resulting solution was evaporated to dryness and the residue recrystallised from methanol/ether mixture to yield N,N'-dimethyl-N"-2-phenylethylguanidine hydriodide, melting point 156°-160°C.

後処理

  1. temperatureunder reflux for eight hours
  2. customThe resulting solution was evaporated to dryness
  3. customthe residue recrystallised from methanol/ether mixture

出典と根拠

ORDレコード
ord-f4ee57d54bcb4c648d3450532234631c
出典データセット
uspto-grants-1976_07
特許番号
US03968243

反応ノート

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