Bromine → 2-[Bromo(nitro)methylidene]-1-methylimidazolidine

HRID 918040ノート

反応式

HRID 918040 の反応式
[CH3:1][N:2]1[CH2:6][CH2:5][NH:4][C:3]1=[CH:7][N+:8]([O-:10])=[O:9].[Br:11]Br>O>[Br:11][C:7]([N+:8]([O-:10])=[O:9])=[C:3]1[NH:4][CH2:5][CH2:6][N:2]1[CH3:1]

参加物

4

反応物 2

HCID 24408BromineHCID 702500461-Methyl-2-(nitromethylidene)imidazolidine2 回

生成物 1

HCID 706389552-[Bromo(nitro)methylidene]-1-methylimidazolidine

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A stirred solution of 3.57 grams of 1-methyl-2(nitromethylene)imidazolidine (Compound 1) in 25 milliliters of water was treated dropwise with 3.99 grams of bromine at room temperature. After 30 minutes, the reaction mixture was extracted with methylene chloride. The extract was dried (MgSO4) and the solvent was evaporated to give 3.0 grams of crude product, melting point 100° (with vigorous decomposition). Recrystallization of the crude product from methylene chloride gave 15, melting point: 97° (explodes).

後処理

  1. extractionthe reaction mixture was extracted with methylene chloride
  2. dry with materialThe extract was dried (MgSO4)
  3. customthe solvent was evaporated
  4. customto give 3.0 grams of crude product, melting point 100° (with vigorous decomposition)
  5. customRecrystallization of the crude product from methylene chloride

出典と根拠

ORDレコード
ord-aba6bbb82a6a497eb5fecfac18c2958d
出典データセット
uspto-grants-1976_07
特許番号
US03969354

反応ノート

読み込み中…