反応式
[F:1][C:2]1[CH:7]=[CH:6][C:5](I)=[CH:4][CH:3]=1.[CH3:9][C:10]([C:12]1[CH:17]=[CH:16][C:15](Br)=[C:14]([N+:19]([O-:21])=[O:20])[CH:13]=1)=[O:11]>CO>[C:10]([C:12]1[CH:17]=[CH:16][C:15]([C:5]2[CH:6]=[CH:7][C:2]([F:1])=[CH:3][CH:4]=2)=[C:14]([N+:19]([O-:21])=[O:20])[CH:13]=1)(=[O:11])[CH3:9]参加物
4
実験手順
4-fluoroiodobenzene and 4-bromo-3-nitroacetophenone were reacted in an analogous manner to that described in Example 1 (a) to give the novel intermediate 4-acetyl-4'-fluoro-2-nitrobiphenyl, m.p. 88° - 90°C. (from methanol). This compound was reduced with stannous chloride in concentrated hydrochloric acid in an analogous manner to that described in Example 1 (b) to give the novel intermediate 4-acetyl-2-amino-4'-fluorobiphenyl, m.p. 88° - 91°C. (from methanol). The amino group in this compound was converted to methoxy in the following way:
出典と根拠
- ORDレコード
- ord-fffb69d45e50446d86828345be52bdd9
- 出典データセット
- uspto-grants-1976_07
- 特許番号
- US03969402
関連ノート
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