関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | (S)-Ethyl 3-amino-3-phenylpropanoate | HCID 915085 | — |
| 反応物 | Potassium alloy, nonbase, K,Na | HCID 16211683 | — |
| 生成物 | (R)-Ethyl 3-amino-3-phenylpropanoate | HCID 915086 | 93.1% |
反応手順
In a 25 ml flask, 13.0 g of D-β-phenylalanine ethyl ester was charged under nitrogen, and sodium-potassium alloy (Na : K = 56 : 44 by weight) (0.1 g) was added thereto. The mixture was stirred at 20°C for 3 hours. The reaction mixture was treated as in Example 11 to give 12.1 g of racemic β-phenylalanine ethyl ester. B.P. 95° to 96°C/0.6 mmHg. [α]D25 -0.1° (neat).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US03970700 |
|---|
| 出典データセット | uspto-grants-1976_07 |
|---|
| ORD ID | ord-d96040b264dc47d38633722070ebf611 |
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| 出典メモ | uspto-grants-1976_07 |
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