Sodium Methoxide → HCID 53801387、化合物
反応式
[CH3:1][O-:2].[Na+].[CH2:4]([C:11]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)(Cl)[C:12]([O:14][CH2:15][CH:16]=[CH2:17])=[O:13])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1>CO>[CH2:4]([C:11]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)([O:2][CH3:1])[C:12]([O:14][CH2:15][CH:16]=[CH2:17])=[O:13])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1参加物
4
実験手順
Into a solution of 1.1 g of sodium methylate in 20 cc of methanol was added a solution of 6.0 g of allyl α-benzyl-α-chlorophenylacetate in 10 cc of methanol under cooling, and the mixture was stirred for 2 hours, whereby white precipitates were deposited. The reaction mixture was poured in water and the resultant was subjected to extraction with ether. The ether extract was washed with an aqueous solution saturated with sodium chloride and dried over sodium sulfate, and thereafter evaporation of ether gave 5.6 g of oily allyl α-benzyl-α-methoxyphenylacetate, nD25 1.5486.