Dimethylformamide → HCID 21521210、化合物

反応式

[N+:1]([C:4]1[CH:5]=[C:6]([CH:12]=[CH:13][CH:14]=1)[N:7]([CH2:10][CH3:11])[CH2:8][CH3:9])([O-:3])=[O:2].P(Cl)(Cl)(Cl)=O.CN(C)[CH:22]=[O:23]>>[N+:1]([C:4]1[CH:5]=[C:6]([N:7]([CH2:10][CH3:11])[CH2:8][CH3:9])[CH:12]=[CH:13][C:14]=1[CH:22]=[O:23])([O-:3])=[O:2]

参加物

反応物 3

HCID 6228Dimethylformamide

HCID 24813Phosphorus oxychloride

HCID 75186Benzenamine, N,N-diethyl-3-nitro-

生成物 1

HCID 21521210HCID 21521210、化合物収率 27%

反応条件

温度: 60 °C

実験手順

38 parts of m-nitrodiethylaniline is introduced into a mixture of 48 parts of phosphorus oxychloride in 120 parts of dimethylformamide. After having been stirred for six hours at 60°C the mixture is poured into ice-water and the precipitate is suction filtered, washed free from acid and recrystallized from acetone. 12 parts (27% of theory) of 2-nitro-4-diethylaminobenzaldehyde having a melting point of 75° to 77°C is obtained. ##SPC15##

後処理

filtrationfiltered
washwashed free from acid
customrecrystallized from acetone

出典と根拠

ORDレコード: ord-70013bcabfc5405d9cc4978b6a11a009
出典データセット: uspto-grants-1976_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US03971821

反応ノート

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