4-Anilino-3-nitro-5-sulphamyl-benzoic acid → 3-Amino-4-piperidino-5-sulphamyl-benzoic acid

HRID 918633ノート

反応式

HRID 918633 の反応式
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([S:19](=[O:22])(=[O:21])[NH2:20])[C:12]=1[N:13]1[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1)[C:7]([OH:9])=[O:8])([O-])=O.N(C1C(S(=O)(=O)N)=CC(C(O)=O)=CC=1[N+]([O-])=O)C1C=CC=CC=1>>[NH2:1][C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([S:19](=[O:21])(=[O:22])[NH2:20])[C:12]=1[N:13]1[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1)[C:7]([OH:9])=[O:8]

参加物

3

反応物 2

HCID 215060714-Anilino-3-nitro-5-sulphamyl-benzoic acidHCID 215061073-Nitro-4-piperidino-5-sulphamyl-benzoic acid

生成物 1

HCID 215061343-Amino-4-piperidino-5-sulphamyl-benzoic acid

実験手順

By substituting 3-nitro-4-piperidino-5-sulphamyl-benzoic acid for the 4-anilino-3-nitro-5-sulphamyl-benzoic acid of Example 9 B, the above compound was obtained with a melting point of 279°C (decomp.) after recrystallization from aqueous methanol.

後処理

  1. customthe above compound was obtained with a melting point of 279°C (decomp.)
  2. customafter recrystallization from aqueous methanol

出典と根拠

ORDレコード
ord-4837ddec877343ac9a16c3795056a215
出典データセット
uspto-grants-1976_07
特許番号
US03971819

反応ノート

読み込み中…