Ethyl 3-benzylamino-5-dimethylsulphamyl-4-phenoxy-benzoate → 3-Benzylamino-5-(n-butylsulphamyl)-4-phenoxy-benzoic acid
反応式
[CH2:1]([NH:8][C:9]1[CH:10]=[C:11]([CH:17]=[C:18]([S:27](=[O:34])(=[O:33])[NH:28][CH2:29][CH2:30][CH2:31][CH3:32])[C:19]=1[O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)[C:12]([O:14]CC)=[O:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(NC1C=C(C=C(S(=O)(=O)N(C)C)C=1OC1C=CC=CC=1)C(OCC)=O)C1C=CC=CC=1>>[CH2:1]([NH:8][C:9]1[CH:10]=[C:11]([CH:17]=[C:18]([S:27](=[O:34])(=[O:33])[NH:28][CH2:29][CH2:30][CH2:31][CH3:32])[C:19]=1[O:20][C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1)[C:12]([OH:14])=[O:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1参加物
3
実験手順
By substituting in step B above ethyl 3-benzylamino-5-(n-butylsulphamyl)-4-phenoxy-benzoate for the ethyl 3-benzylamino-5-dimethylsulphamyl-4-phenoxy-benzoate, and after recrystallization from ethanol, the aove compound was obtained with a melting point of 212°C.
後処理
- customafter recrystallization from ethanol
- customthe aove compound was obtained with a melting point of 212°C.