2-Fluoro-5-(trifluoromethoxy)benzylamine → 6-Bromo-N-(2-fluoro-5-(trifluoromethoxy)benzyl)imidazo[1,2-a]pyridine-2-carboxamide
反応式
[F:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:9]([F:12])([F:11])[F:10])=[CH:4][C:3]=1[CH2:13][NH2:14].[Br:15][C:16]1[CH:17]=[CH:18][C:19]2[N:20]([CH:22]=[C:23]([C:25](OCC)=[O:26])[N:24]=2)[CH:21]=1>>[Br:15][C:16]1[CH:17]=[CH:18][C:19]2[N:20]([CH:22]=[C:23]([C:25]([NH:14][CH2:13][C:3]3[CH:4]=[C:5]([O:8][C:9]([F:11])([F:12])[F:10])[CH:6]=[CH:7][C:2]=3[F:1])=[O:26])[N:24]=2)[CH:21]=1参加物
3
実験手順
The title compound was prepared by essentially following the same procedures described for Intermediate I, using (2-fluoro-5-(trifluoromethoxy)phenyl)methanamine and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.
出典と根拠
- ORDレコード
- ord-32e750e570a842d290e83e223bce9667
- 出典データセット
- uspto-grants-2016_03
- 特許番号
- US09271969B2
反応ノート
読み込み中…