2-Bromoimidazo[2,1-b]thiazole-6-carboxylic acid → 2-Bromo-N-(3-chloro-4-(trifluoromethoxy)benzyl)imidazo[2,1-b]thiazole-6-carboxamide
反応式
[Cl:1][C:2]1[CH:3]=[C:4]([CH2:13][NH2:14])[CH:5]=[CH:6][C:7]=1[O:8][C:9]([F:12])([F:11])[F:10].[Br:15][C:16]1[S:20][C:19]2=[N:21][C:22]([C:24](O)=[O:25])=[CH:23][N:18]2[CH:17]=1>>[Br:15][C:16]1[S:20][C:19]2=[N:21][C:22]([C:24]([NH:14][CH2:13][C:4]3[CH:5]=[CH:6][C:7]([O:8][C:9]([F:11])([F:12])[F:10])=[C:2]([Cl:1])[CH:3]=3)=[O:25])=[CH:23][N:18]2[CH:17]=1参加物
3
実験手順
The title compound was prepared by essentially following the same procedures described for Intermediate XLVI, using (3-chloro-4-(trifluoromethoxy)phenyl)methanamine and 2-bromoimidazo[2,1-b]thiazole-6-carboxylic acid as starting materials.
出典と根拠
- ORDレコード
- ord-9ce2e8e86d5542aeb6850d95ab1b5cd8
- 出典データセット
- uspto-grants-2016_03
- 特許番号
- US09271969B2
反応ノート
読み込み中…