2-Fluoro-5-(trifluoromethoxy)benzylamine → 2-Bromo-N-(2-fluoro-5-(trifluoromethoxy)benzyl)imidazo[2,1-b]thiazole-6-carboxamide
反応式
[F:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:9]([F:12])([F:11])[F:10])=[CH:4][C:3]=1[CH2:13][NH2:14].[Br:15][C:16]1[S:20][C:19]2=[N:21][C:22]([C:24](O)=[O:25])=[CH:23][N:18]2[CH:17]=1>>[Br:15][C:16]1[S:20][C:19]2=[N:21][C:22]([C:24]([NH:14][CH2:13][C:3]3[CH:4]=[C:5]([O:8][C:9]([F:11])([F:12])[F:10])[CH:6]=[CH:7][C:2]=3[F:1])=[O:25])=[CH:23][N:18]2[CH:17]=1参加物
3
実験手順
The title compound was prepared by essentially following the same procedures described for Intermediate XLIV, using (2-fluoro-5-(trifluoromethoxy)phenyl)methanamine and 2-bromoimidazo[2,1-b]thiazole-6-carboxylic acid as starting materials.
出典と根拠
- ORDレコード
- ord-1a181661a7224b2abb085616cd1cbf58
- 出典データセット
- uspto-grants-2016_03
- 特許番号
- US09271969B2
反応ノート
読み込み中…