Maleimide → 3-(5-methyl-1H-indol-3-yl)pyrrolidine-2,5-dione

関与物質

反応手順

5-Methyl indole (10 g, 76 mmol) and maleimide (7.4 g, 76 mmol) in 77 mL of glacial acetic acid was heated at 90° C. for 24 h. The reaction mixture was cooled to RT, and the acetic acid was evaporated under reduced pressure. The residue was suspended in diethyl ether and filtered to obtain solid product (7 g).

情報源と証拠