化工社化工社 化学情報印刷レポート · 研究参考用
Methanol → Methyl 3-phenoxypropionate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | 3-Phenoxypropionic acid | HCID 81596 | — |
| 触媒 | Sulfuric Acid | HCID 1118 | — |
| 生成物 | Methyl 3-phenoxypropionate | HCID 347927 | 92.5% |
反応手順
3-phenoxypropionic acid (5.0 g, 30 mmol) was dissolved in MeOH (12 mL) and H2SO4 (18 M, 3 drops) was added. The mixture was place in the microwave reactor (T: 140° C., t: 5 min). The solvent was evaporated, the mixture was partitioned in EtOAc (30 mL) and NaOH (2N, 20 mL). The organic phase was dried over MgSO4, filtered, and evaporated to give methyl 3-phenoxypropanoate (5.0 g, 27.7 mmol, 92.5%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09272996B2 |
| 出典データセット | uspto-grants-2016_03 |
| ORD ID | ord-82e83209270646fab7c83a246bd433a0 |
| 出典メモ | uspto-grants-2016_03 |