Dichloromethane → Methyl 3-(4-formylphenyl)propanoate
反応式
C[CH:2]([CH2:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][OH:14])=[CH:9][CH:8]=1)[C:3]([OH:5])=[O:4].[CH2:15](Cl)Cl>[O-2].[O-2].[Mn+4]>[CH:13]([C:10]1[CH:11]=[CH:12][C:7]([CH2:6][CH2:2][C:3]([O:5][CH3:15])=[O:4])=[CH:8][CH:9]=1)=[O:14]参加物
4
実験手順
To a solution of Intermediate B (300 mg, 1.54 mmol) in DCM (25 mL) was added manganese dioxide (2.98 g, 34 mmol). The mixture was stirred for 15 minutes, and then filtered through Celite and washed with additional DCM (100 mL). The filtrate was concentrated to yield the desired product. This was used directly in the next stage without further purification or characterisation.
後処理
- filtrationfiltered through Celite
- washwashed with additional DCM (100 mL)
- concentrationThe filtrate was concentrated
出典と根拠
- ORDレコード
- ord-7b2898cfb37a477caca0a6e141f6acf2
- 出典データセット
- uspto-grants-2016_03
- 特許番号
- US09273003B2
反応ノート
読み込み中…