化工社化工社 化学情報印刷レポート · 研究参考用
5-Nitrothiophene-2-carboxaldehyde → 5-Nitro-2-thiophenecarbaldehyde 2-(6-trifluoromethyl-1,3-benzothiazol-2yl)hydrazone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-Nitrothiophene-2-carboxaldehyde | HCID 78281 | — |
| 反応物 | 5-Nitro-2-furaldehyde 2-(1,3-benzothiazole-2-yl)hydrazone | HCID 2856671 | — |
| 反応物 | 2-Hydrazino-6-trifluoromethyl-benzothiazole | HCID 24728955 | — |
| 生成物 | 5-Nitro-2-thiophenecarbaldehyde 2-(6-trifluoromethyl-1,3-benzothiazol-2yl)hydrazone | HCID 86664231 | — |
反応手順
The compound 3h was prepared according procedure described for 3a by employing 5-nitrothiophen aldehyde (157 mg, 1 mmol) and 2-hydrazino-6-trifluoromethyl-benzothiazole (233 mg, 1 mmol) at 70° C. for 2 h (yield 312 mg, 84%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09273039B2 |
| 出典データセット | uspto-grants-2016_03 |
| ORD ID | ord-a13763deafa0473cb758d16ed7eaa7b1 |
| 出典メモ | uspto-grants-2016_03 |