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5-Nitrothiophene-2-carboxaldehyde → 5-Nitro-2-thiophenecarbaldehyde 2-(6-trifluoromethoxy-1,3-benzothiazol-2yl)hydrazone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-Nitrothiophene-2-carboxaldehyde | HCID 78281 | — |
| 反応物 | 5-Nitro-2-furaldehyde 2-(1,3-benzothiazole-2-yl)hydrazone | HCID 2856671 | — |
| 反応物 | 2-Hydrazinyl-6-(trifluoromethoxy)-1,3-benzothiazole | HCID 10422158 | — |
| 生成物 | 5-Nitro-2-thiophenecarbaldehyde 2-(6-trifluoromethoxy-1,3-benzothiazol-2yl)hydrazone | HCID 86664233 | — |
反応手順
The compound 3j was prepared according procedure described for 3a by employing 5-nitrothiophen aldehyde (157 mg, 1 mmol) and 2-hydrazino-6-trifluoromethoxy-benzothiazole (249 mg, 1 mmol) at 70° C. for 2 h (yield 219 mg, 75%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09273039B2 |
| 出典データセット | uspto-grants-2016_03 |
| ORD ID | ord-f77a14a2eeaf45e7b6abb5c9beed0994 |
| 出典メモ | uspto-grants-2016_03 |