5-Nitrothiophene-2-carboxaldehyde → 5-Nitro-2-thiophenecarbaldehyde 2-(6-chloro-1,3-benzothiazol-2yl)hydrazone

HRID 919379

反応式

HRID 919379 の反応式
S1C2C=CC=CC=2N=C1NN=CC1OC([N+]([O-])=O)=CC=1.[N+:21]([C:24]1[S:28][C:27]([CH:29]=O)=[CH:26][CH:25]=1)([O-:23])=[O:22].[NH:31]([C:33]1[S:34][C:35]2[CH:41]=[C:40]([Cl:42])[CH:39]=[CH:38][C:36]=2[N:37]=1)[NH2:32]>>[Cl:42][C:40]1[CH:39]=[CH:38][C:36]2[N:37]=[C:33]([NH:31][N:32]=[CH:29][C:27]3[S:28][C:24]([N+:21]([O-:23])=[O:22])=[CH:25][CH:26]=3)[S:34][C:35]=2[CH:41]=1

参加物

4

反応物 3

HCID 782815-Nitrothiophene-2-carboxaldehydeHCID 7371976-Chloro-2-hydrazinyl-1,3-benzothiazoleHCID 28566715-Nitro-2-furaldehyde 2-(1,3-benzothiazole-2-yl)hydrazone

生成物 1

HCID 866642355-Nitro-2-thiophenecarbaldehyde 2-(6-chloro-1,3-benzothiazol-2yl)hydrazone

実験手順

The compound 3n was prepared according procedure described for 3a by employing 5-nitrothiophen aldehyde (157 mg, 1 mmol) and 2-hydrazino-6-chloro-benzothiazole (199 mg, 1 mmol) at 70° C. for 2 h (yield 287 mg, 85%).

後処理

  1. customat 70° C.
  2. customfor 2 h

出典と根拠

ORDレコード
ord-dcd6ac6ae27a4109be212ec35f340e81
出典データセット
uspto-grants-2016_03
特許番号
US09273039B2

関連ノート

読み込み中…