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(3-Fluoro-4-((6-(trifluoromethyl)-3-pyridinyl)oxy)phenyl)methanol → 8-((3-fluoro-4-((6-(trifluoromethyl)pyridin-3-yl)oxy)benzyl)oxy)-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (3-Fluoro-4-((6-(trifluoromethyl)-3-pyridinyl)oxy)phenyl)methanol | HCID 66825479 | — |
| 反応物 | 8-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-one | HCID 71743471 | — |
| 生成物 | 8-((3-fluoro-4-((6-(trifluoromethyl)pyridin-3-yl)oxy)benzyl)oxy)-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one | HCID 71236659 | — |
反応手順
The title compound was prepared by a procedure similar to that described for E1 starting from 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one and (3-fluoro-4-((6-(trifluoromethyl)pyridin-3-yl)oxy)phenyl)methanol.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09273054B2 |
| 出典データセット | uspto-grants-2016_03 |
| ORD ID | ord-f94746cb485d42738b4631970cc5fb1d |
| 出典メモ | uspto-grants-2016_03 |